CLOVES Syndrome Awareness Day
CLOVES Syndrome Awareness Day is observed annually on 3 August to increase understanding of this rare genetic disorder characterised by tissue overgrowth and vascular malformations. The syndrome results from mutations in the PIK3CA gene and is part of the PIK3CA-related overgrowth spectrum (PROS). First described in 1867 and officially recognised in 2007, CLOVES affects approximately 200 people worldwide. Awareness efforts include promoting solidarity through green symbols and supporting research and patient resources. In Australia, specialised clinical services and support schemes assist individuals living with CLOVES and related conditions.
